技能详情（站内镜像，无评论）
作者：AIpoch @AIPOCH-AI
许可证：MIT-0
MIT-0 ·免费使用、修改和重新分发。无需归因。
版本：v1.0.0
统计：⭐ 0 · 237 · 0 current installs · 0 all-time installs
⭐ 0
安装量（当前） 0
🛡 VirusTotal ：可疑 · OpenClaw ：可疑
Package：aipoch-ai/variant-annotation
安全扫描（ClawHub）
- VirusTotal ：可疑
- OpenClaw ：可疑
OpenClaw 评估
The skill largely matches its stated purpose (querying ClinVar/dbSNP and producing ACMG-based annotations) but the README claims additional data sources and prediction tools (gnomAD, SIFT/PolyPhen/CADD, etc.) that are not clearly implemented in the shipped code — review before trusting outputs or uploading sensitive genomic data.
目的
Name/description and the code align on querying ClinVar and dbSNP via NCBI E-utilities and computing ACMG scores. However, SKILL.md promises population allele frequencies from gnomAD/ExAC/1000G and functional predictions (SIFT, PolyPhen, CADD). The provided code shows only NCBI E-utilities calls (ClinVar and dbSNP) and does not include integrations or downloads for gnomAD, ExAC, 1000 Genomes, or functional prediction APIs, so those claimed cap…
说明范围
SKILL.md instructs local usage (importing the Python class or running the script) and mentions batch/VCF input. The runtime instructions and code only call NCBI endpoints; they do not instruct reading unrelated system files or external endpoints beyond NCBI. That scope is appropriate, but the doc's broad list of data sources and computed outputs is larger than what the code implements — the agent could therefore report values that are estimate…
安装机制
This is instruction-only / script-based with no install spec and a minimal requirements.txt (dataclasses). No external installers, downloads, or unusual repository fetches are present — low install risk.
证书
No required environment variables or credentials are declared. The VariantAnnotator constructor accepts an optional NCBI API key (appropriate and optional for higher rate limits). No unrelated secrets or system config paths are requested.
持久
The skill does not request 'always: true' and does not modify other skills or system-wide agent settings. It runs as a standalone script/class and does not demand persistent elevated privileges.
安装（复制给龙虾 AI）
将下方整段复制到龙虾中文库对话中，由龙虾按 SKILL.md 完成安装。
请把本段交给龙虾中文库（龙虾 AI）执行：为本机安装 OpenClaw 技能「Variant Annotation」。简介：Query and annotate gene variants from ClinVar and dbSNP databases. Trigger when…。
请 fetch 以下地址读取 SKILL.md 并按文档完成安装：https://raw.githubusercontent.com/openclaw/skills/refs/heads/main/skills/aipoch-ai/variant-annotation/SKILL.md
（来源：yingzhi8.cn 技能库）SKILL.md
暂无本地缓存内容，可在后台执行详情同步。